Wednesday, May 31, 2023

The Magic of the Silver Screen: Our Brains on Film

Whether it's the magical world of Harry Potter, action-packed Marvel features, or the emotional epic that is Titanic, no matter who you are there is a film for you. My fascination with film began at a young age, jump started by movies like Ponyo, Wall-E, and Spider-Man. Even at the age of 5 or 6, these movies were extremely impactful, stirring up emotions that I lacked the vocabulary to describe. Now at 17, I still am infatuated with film but I am also interested in what makes them so magical. If we know it's not real, why is Friday the 13th so scary, The Green Mile so sad, and Superbad so funny. The answer lies in film's relationship with the way we all interpret and understand the world around us, the real magic-maker: our brain!


Many consider film to be the peak form of art as it incorporates image and sound to serve its storytelling purpose. This means that it has a unique effect on the brain. It stimulates the areas of the brain that processes visual and auditory information and several areas that signify emotions such as fear, compassion, or self-awareness. Studies conducted by Princeton University's Uri Hasson has made great advances in understanding film's effect on the brain. Subjects were exposed to clips from different films and TV shows like Bang! You're Dead, The Good, The Bad, and The Ugly, Dog Day Afternoon, and Curb Your Enthusiasm as well as footage from Washington Square Park in NYCwith varying effects. The study uses ISC (Inter Subject Correlation) which is merely a measure of how much of the brain activity was shared among the participants. It showed that across films with more deliberate editing and emotional scenes, there was a ISC measure of 65 percent of the participants compared to a more freeform, true to life approach taken by Curb Your Enthusiasm which came into about 18 percent. The structured, edited films scored significantly higher in ISC than the unstructured, minimally edited films. This study shows us the collective effects of film and specifically the importance of film editing and cinematography. Hard editing and structure is used to pull the viewer's attention to a specific subject or idea. Correct usage of both allows the viewer to dissect the scene and understand its point and value to the story. Subjects who watched edited, emotion driving clips exhibited similar brain activity and emotion responses. So, now we know that film with meaningful editing, whether it is to build suspense or draw out an emotional response from the viewer, is a contributing factor of the reaction to a film. 

But film is much more than editing, and it is about more than collective responses. So, how does film effect the individual? A study conducted by Phil Carlsen and Devon Hubbard at Mindsign, a company that invests in neurocinematics, investigates activity in different areas of the brain while watching a film. Using a functional magnetic resonance imaging (fMRI) machine, which measures blood flow within the brain which corresponds to brain activity. In this study, several observations point directly to the relationship between the screen and the mind. Areas of the brains like the frontal cortex, ventromedial prefrontal cortex, amygdala, fusiform gyri, and insula were stimulated during the viewings. These areas are important for functions like emotion, facial recognition, memory, self-awareness, and attention. This shows the viewer's brain being stimulated in order to deconstruct a complex series of shots and sounds to create a story. And within this story, the brain can connect as we see when the insula or ventromedial prefrontal cortex are stimulated. This study shows us the specific areas and functions of the brain that makes movie going so enjoyable for viewers. 

So there we have it, the real magic ingredient in the film industry isn't the actors, cinematography, costumes, or even the music. It's the brain. The brain allows for information to be taken from the big screen, processed and analyzed, and then connect with us on an extremely personal level. Neurocinematics is a growing field of interest between scientists and companies and has practical uses in the industry. Trailers, TV clips and more have been analyzed by ISC ratings to see which cut is the most stimulating to the viewer's brain. It is a young field but has a lot of potential for the movie making business in the future. Even without it, we have found a way to make countless impactful, touching films since the technology was first developed in 1895. Film is an expression of human emotions that is like no other. It connects, inspires, and brings joy to people all around the world. But film would be nothing without the hard work of our brains. Film will always have a special place in my heart...and brain.


Monday, May 29, 2023

No Pain, No Gain

I know many of you reading this right now workout almost daily and have goals you would like to reach. Me, like many others, love to lift and are fascinated, yet troubled by the science behind muscle growth and getting stronger. 

Clipart of Someone Doing and Over-head Squat

What is being sore?

More than likely there has been a point in your life where you have been sore. Maybe during preseason, after not working out for a while, or you just did an incredibly hard work out, but what is muscle soreness? 

Simply put, soreness is the pain that you feel from overworking or pushing your muscles to their limits. From a science standpoint, it sounds a little different. Soreness is when your muscle and the connective tissue surrounding it are damaged during exercise. This may sound like a bad thing, but it is actually not! This soreness actually causes hypertrophy.


Photo Depicting a Sore Quad

So, what is hypertrophy?

Hypertrophy is building muscle, but how does that process work? 

During a workout your muscle cells tear and post-workout your body will repair or rebuild those muscle fibers that were torn. To rebuild those fibers, your body will fuse your muscle fibers together, to make new fibers. These create new and large amounts of myofibril that are thicker and stronger than the original ones, making you stronger. 

There is one cell, though, that is responsible for building onto the muscle in your muscle cells. It is the satellite cell. Satellite cells are cells in between two membranes of muscle fibers and many people say that they act as stem cells. On a molecular level, they add nuclei to muscle cells which makes them grow. 

It is important to note that muscle cells are quite peculiar. They are multi-nucleated (have more than one nucleus) and rarely, if ever, divide. This is rare for a cell as cells are always going through mitosis and replicating. These muscle cells can not divide because they are multi-nucleated and keep growing larger. The reason why they have several nuclei (plural of nucleus) is to maximize their internuclear distances (distance between nuclei) which will make their bonds weaker which allows them to grow so large. So, you are not gaining more muscle cells, you are making your muscle cells larger.



Diagram of Myofibril
Photo Showing Muscle Hypertrophy (Growth)

Photo Showing Skeletal Muscle Under A Microscope

Why do you lose muscle so quickly?

You may have experienced a time where you could not get in the gym for a couple weeks or you had a short injury; and even in this short branch of time you could feel yourself having become weaker, although you were not visibly weaker. This can be explained by both your brain and your muscles. 

To lift weights you have to be somewhat coordinated, and it takes muscle memory for you to be able to improve your coordination. In turn, this affects your movement of the weights. So, if you take some time off the good news is that you do NOT lose muscle because (as we discussed earlier) the muscle fibers you previously built are still intact, but you lose some muscle memory which is why it feels heavier to move the weights again. This can be further explained by disuse atrophy. To break it down simply, disuse means not in use, the prefix "a-" means not, and the suffix "-trophy" means nutrition/growth, so it means you do not have muscle growth from not using your muscles! From a science standpoint, when you stop using your muscles your body will not take care of your muscles because that would be wasting energy. Alternatively, your body will break down these muscles causing you to lose strength.

Why are some people stronger than others?

Well, depending on the situation there are a number of answers to this question: some people work out more often, some people work out harder, and some people just have better genetics. So, the simple answer to this question is genetics and there are several studies to support it. With this in mind, if you are interested in getting stronger, knowing your genotype (the genetic makeup of an organism) can help you understand your body and know what types of workouts you should do to achieve your goals. You may even have different genotypes than your relatives, so if you are doing the same workouts as your sibling and not seeing improvement like they are, the likelihood is that you have different genotypes in your muscle cells and all cells!

What can you do before and after exercising to make you less sore?

Although soreness can make you feel accomplished, there are certain times (game day) where you do not want to be sore because it can limit your performance. Luckily, there are ways to reduce soreness and in turn they also lower your risk of injury.

Warming up/cooling down and stretching are both incredibly helpful ways to reduce soreness and risk of injury. Warming up allows your muscles to get ready for what is next by increasing the blood flow in them. Cooling down helps with heart rate, blood flow, and blood pressure. 

Another way you can reduce your soreness is by not doing hard workouts, heavy weights, or high reps. Also, using improper technique can make you sore because you might start targeting muscles you did not  mean too, so you did not warm those muscles up properly.

More things you can do are drink a sufficient amount of water, ice your muscles, take an ice bath, use the heating pad on your muscles, and/or take a hot shower. Drinking water is important for your all around health, but when it comes to muscles, water is important for energy, loosening of joints, and limiting dizziness, tiredness, and headaches. Icing your muscles is good for decreasing inflammation and pain. On the opposite side, heating your muscles is good for reducing pain, healing damaged tissue, and reducing muscle tension.


Photo Showing A Woman In A Lunge Position, Stretching


To put this all together, when not working out for a little while, you do not lose strength, you lose muscle memory. The journey of getting stronger is different for everyone. There are ways to reduce your soreness, but you can not make it disappear entirely. Lastly, soreness is good and leads to hypertrophy; no pain, no gain.